A guided chatbot-based psychological intervention for psychologically distressed older adolescents and young adults: a randomised clinical trial in Jordan

Richard A. Bryant, Anne M. de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Hadeel Afar, Chiara Servili, Dusan Hadzi‑Pavlovic, Mark van Ommeren, Kenneth Carswell
15
January
2026
Output type
Journal article
Location
Jordan
Focus areas
Mental health and psychosocial support (MHPSS)
Topics
No items found.
Programme
Humanitarian Research
Organisations
World Health Organisation

This randomised controlled trial compared a 10-session chatbot intervention with 5 weekly brief support calls (STARS) to enhanced usual care (EUC) in distressed young adults in Jordan (N = 344).

Primary outcome was change in anxiety and depression severity assessed at baseline by the Hopkins Symptom Checklist (HSCL), 1-week post-treatment, and 3 months after treatment (primary outcome timepoint), as well as secondary outcome measures of psychological distress, personally identified problems, functional impairment, wellbeing and perceived agency. At the 3-month assessment, relative to EUC participants enrolled in STARS reported greater reductions of anxiety (effect size, 0.70) and depression (size, 0.61), as well as greater reductions in psychological distress, personally identified problems, functional impairment and greater improvement in wellbeing and sense of agency. Similar levels of efficacy were retained even for those with more severe symptom levels.

This guided chatbot offers a scalable psychological intervention that can be implemented to increase access to evidence-based mental health care.

This publication relates to R2HC funded study; Effectiveness of a self-help chatbot for conflict-affected youth

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World Health Organisation