Eastern Democratic Republic of the Congo Mpox (ECOPOX) Vaccine Acceptance Initiative

Team members Prof Dalau Nkamba and Dr. Georges Mutenge in Maluku Region, Kinshasa Province en route to administer a vaccination coverage survey among hard-to-reach communities, November 2024. Photo: Sydney Merritt.

Project overview

The ECOPOX project aims to assess mpox knowledge, risk perception, and vaccine acceptability among at-risk populations in DRC to guide community-specific vaccine deployment and sensitisation campaigns.

Countries
Democratic Republic of Congo
Organisations
University of Manitoba
Partners
University of California Los Angeles (UCLA), Institut National de Recherche Biomédicale (INRB)
Area of funding
Humanitarian Research
Grant amount
£123,005
Start date
01
January
2025
End date
31
October
2025
Project length (in months)
10
Funding calls
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Focus areas
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Topics
Communicable diseases
Status
Live

Project solution

This project offers [specific solution or intervention] to tackle [challenge]. By implementing [strategies, tools, or innovations], the project aims to achieve [desired outcomes]. The approach is designed to [specific actions or methods] to bring about meaningful change in [community, region, or issue area].

Expected outcomes

This project aims to achieve [specific outcomes], such as [measurable results, improvements, or changes]. The expected impact includes [benefits to the target community, advancements in research or innovation, or long-term effects]. By the end of the project, we anticipate [specific changes or milestones] that will contribute to [broader goals or objectives].

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Principal Investigators: Jason Kindrachuk, University of Manitoba; Anne W Rimoin, University of California Los Angeles (UCLA); Placide Mbala-Kingebeni, National Institute of Biomedical Research (INRB), Democratic Republic of the Congo (DRC)

Purpose

The public health burden of mpox has been steadily increasing in the DRC since the cessation of the smallpox vaccine and represents a growing burden of morbidity among the population. Simultaneously, vaccine coverage rates in the DRC are consistently below required thresholds. This is in large part due to the underfunding of public health, the lack of necessary health infrastructure, and the logistically challenge terrain. Long-term mpox response will rely on vaccination as a primary intervention, yet there exists a dearth of information about how best to disseminate a vaccine when a targeted rollout strategy is required logistically. ECOPOX will estimate mpox risk among key populations and record key attitudes and uptake behaviours that will be essential to successful vaccination campaigns in the future.

Expected outcomes

This ECOPOX investigation includes three primary outcomes:

  1. Design community-specific and respectful assessment tool through focused community engagement and collaboration with peer leaders.
  2. Assess community knowledge, sentiment, risk perception and stigmas around mpox infection and prevention.
  3. Analyse vaccine acceptability across among at-risk populations in rural and urban communities to guide vaccine deployment and sensitisation campaigns.

Through long-term partnerships and collaborations between our team members, stakeholders and decisionmakers, we aim to engage in truly translational research that supports improved identification of cases and improved vaccination coverage among at-risk populations.

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Project delivery & updates

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Resources

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Communicable diseases
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University of Manitoba
Democratic Republic of Congo