Turkey and Syria earthquake: evidence-based innovations and guidance for acute crisis response.

We are Elrha, a force for change in the humanitarian community. The research and innovation we support equips the humanitarian community with the knowledge of what works, so people affected by crises get the right help when they need it most.
Our purpose is clear: to empower the humanitarian community to improve humanitarian response. We make this happen by supporting and championing the outcomes of robust research and proven innovations.
We empower the humanitarian community. Find out how we can support you...

4 Results for Health Topics

4.1 Communicable disease control

4.1.3 Poliomyelitis

  • In total, 6 papers were included in the review. The intervention in each study was either oral polio vaccine (OPV) or inactivated polio vaccine (IPV).
  • 2/6 papers described vaccine delivery without any relation to health outcomes, while another significant body of literature focused on refugees in middle and high income countries.
  • Only six studies met the inclusion criteria of this review, three of these studies were graded as high quality (O’Reilly 2014, Aaby 2005, Aaby 2002).
  • The remaining three studies, while assessing coverage and not directly measuring health outcomes (e.g. virological markers of uptake), were included as the calculation of cost per child is also an outcome of interest (Sheikh 2014, MMWR 2014).
  • One high quality retrospective case-control analysis has provided the polio community with amongst its best estimates of how and where to target efforts in these settings (O’Reilly 2014).
  • In terms of effectiveness, this decade-long analysis of children -14 years in Afghanistan and Pakistan – indicated a significant reduction in polio and acute flaccid paralysis (AFP) incidence. It also demonstrated that mono- and bivalent formulations of OPV work equally well in this population and setting.
  • Two high quality papers from Guinea Bissau provided morbidity and mortality estimates in relation to measles and IPV; both vaccines were part of a RCT that had been severely interrupted due to civil war (Aaby 2002, 2005)

These studies, both presenting data gathered during interruptions due to war, demonstrated that OPV is associated with significantly less mortality and hospitalizations, particularly in children aged 6 months or younger. Further, studies indicate a difference in mortality between males and females but the results are inconclusive overall: one study found a higher morality in females than males for IPV, while another found no difference between males and females for OPV.

View Publication View Executive Summary View Executive Summary - French

Subscribe to our newsletters....

Elrha © 2018 - 2023 Elrha is a registered charity in England and Wales (1177110). KEEP IN TOUCH Want to stay up to date with our latest updates? Sign up to our newsletters
Elrha Please upgrade your browser

You are seeing this because you are using a browser that is not supported. The Elrha website is built using modern technology and standards. We recommend upgrading your browser with one of the following to properly view our website:

Windows Mac

Please note that this is not an exhaustive list of browsers. We also do not intend to recommend a particular manufacturer's browser over another's; only to suggest upgrading to a browser version that is compliant with current standards to give you the best and most secure browsing experience.