Shaping the future: Our strategy for research and innovation in humanitarian response.

A global organisation that finds solutions to complex humanitarian problems through research and innovation..
Our purpose is clear: we work in partnership with a global community of humanitarian actors, researchers and innovators to improve the quality of humanitarian action and deliver better outcomes for people affected by crises.
We empower the humanitarian community. Find out how we can support you...

4 Results for Health Topics

4.1 Communicable disease control

4.1.2 Malaria

  • Over half (55%, 62/151) of the 151 CD interventions that met the inclusion criteria of this review were conducted against malaria.
  • Nearly half (>45%) of these studies were randomized-controlled trials, most (>80%) of high quality, indicating a higher degree of confidence in their results compared to other less rigorous designs.
  • All (100%) malarial interventions in this review occurred in populations displaced as a result of armed conflict.
  • 20 vector control interventions met the inclusion criteria of this review.
  • Insecticide-treated nets (ITNs) (N=7) were the most frequently studied intervention in these settings, followed by insecticide spraying (IS) and a variety of insecticide-treated surfaces (clothes, tents, sheeting, cattle).
  • Nearly half of the vector control interventions (8/20, 40%) were conducted in northwestern Pakistan among Pakistani natives, Afghan residents, and Afghan refugees living in camp and non camp settings; the remaining research was equally split between Southeast Asia (6/20) and Africa (6/20).
  • Half (50%) of the 20 vector control interventions were RCTs, with the majority of these (80%) graded as high quality.
  • 42 human-targeted interventions met the inclusion criteria of this review.
  • Anti-malarials (N=61) were the most frequently studied intervention in these settings, although one study of a malaria vaccine was included.
  • Three quarters of the human targeted interventions (32/42, 76%) were conducted in Southeast Asia, with over 90% (30/32) of research conducted in these areas by research groups on the Thai Burmese or Thai-Cambodian borders.
  • Three quarters (76%) of the 42 interventions were RCTs of some design, with the majority of these (75%) graded as high quality.
  • In terms of effectiveness, insecticide treated nets, tents, and clothes were found to be significantly more effective than their untreated counterparts (See Malaria vector table). However, these findings varied by region and over time, likely related to changes in vector and host parasite patterns over the inclusion years of this review.
  • This review included 14 studies that included some component of genetic testing for resistance genes to various therapies (e.g. chloroquine), the majority (75%) of which were conducted in Thailand. The majority of studies (65%) included supervised treatment, which provided significantly better ACPR outcomes than non-supervised treatment.


View Publication View Executive Summary View Executive Summary - French HHER 2021 Update

Subscribe to our newsletters....

Elrha © 2018 - 2024 Elrha is a registered charity in England and Wales (1177110). KEEP IN TOUCH Want to stay up to date with our latest updates? Sign up to our newsletters
Elrha Please upgrade your browser

You are seeing this because you are using a browser that is not supported. The Elrha website is built using modern technology and standards. We recommend upgrading your browser with one of the following to properly view our website:

Windows Mac

Please note that this is not an exhaustive list of browsers. We also do not intend to recommend a particular manufacturer's browser over another's; only to suggest upgrading to a browser version that is compliant with current standards to give you the best and most secure browsing experience.