Investigation of HEV Transmission Dynamics and Epidemic Evolution to Improve Outbreak Control Efforts Among Emergency Affected Population
Grant awarded: £389,711
Lead organisation: CDC Foundation
Partnering organisations: Centers for Disease Control (CDC); London School of Hygiene and Tropical Medicine; United Nations High Commissioner for Refugees (UNHCR)
Project length: 2015-2017
Study locations: Worldwide (Likely to be East/Central Africa)
Principal Investigator: Dr Thomas Handzel, CDC Foundation
Determine primary routes of hepatitis E virus (HEV) transmission and spread through epidemiologic and environmental investigations during a HEV outbreak among emergency affected persons, including pregnant women. The research will also determine the effectiveness of chlorine disinfection to inactivate HEV.
Describe the spread of HEV throughout the camp and within households, describe risk factor for HEV acquisitions through epidemiologic and environmental investigations, determine susceptibility of HEV to chlorine, recommend specific interventions that reduce HEV transmission among current and future emergency-affected populations.